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Results We included a population of 711,783 people with a first-time GLP-1 RA prescription who have overweight or obesity

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Schedule (Once Weekly Injection) Upper limit: 12 mg per week is the highest dose used in the major published clinical trials (Phase 2 obesity, Phase 2 type 2 diabetes, and the Phase 3 TRIUMPH-4 and TRANSCEND-T2D-1 studies)

The lack of FDA approval also means that definitive safety and efficacy trials are still forthcoming

A key secondary endpoint was the amount of weight lost